Tadalafil, sold most widely as Cialis, is a PDE5 inhibitor used for erectile dysfunction and benign prostatic hyperplasia. This guide covers how it works, what a standard course looks like, and how ShiningRX supplies it to trade buyers and consumers in the USA, UK and Australia.
Key takeaways
- Tadalafil is a PDE5 inhibitor indicated for erectile dysfunction and benign prostatic hyperplasia.
- Typical dosing: 10 mg on demand, or 2.5–5 mg once daily for spontaneity.
- Onset is 30–120 minutes; effect lasts up to 36 hours.
- Most reported side effects are back pain and other mild, self-limiting reactions.
- Store 15–30 °C, dry, original blister.
Tadalafil at a glance
| Attribute | Detail |
|---|---|
| Drug class | PDE5 inhibitor |
| Common brand | Cialis |
| Licensed use | erectile dysfunction and benign prostatic hyperplasia |
| Available strengths | 2.5 mg, 5 mg, 10 mg, 20 mg |
| Dosage form | film-coated tablet |
| Typical onset | 30–120 minutes |
| Duration / dosing interval | up to 36 hours |
| Storage | 15–30 °C, dry, original blister |
How Tadalafil works
As a PDE5 inhibitor, Tadalafil acts on the pathway that drives erectile dysfunction and benign prostatic hyperplasia. The pharmacological effect is dose-related, which is why prescribers begin at the lowest useful strength and adjust on response rather than starting at the maximum. In practice that means 10 mg on demand, or 2.5–5 mg once daily for spontaneity
Starting a Tadalafil course
- 1
Clinical assessment
Confirm the indication for erectile dysfunction and benign prostatic hyperplasia, review comorbidities and check the contraindication list before the first dose.
- 2
Initiate at the standard dose
10 mg on demand, or 2.5–5 mg once daily for spontaneity
- 3
Review at the first checkpoint
Reassess once the expected onset window of 30–120 minutes has passed and document tolerability.
- 4
Titrate or switch
If response is partial and tolerance is good, step up within the licensed range; if tolerance is poor, consider Sildenafil.
Safety profile in brief
Commonly reported effects include back pain, myalgia, headache, reflux, nasal congestion. Tadalafil should be avoided in nitrate users and men with uncontrolled hypotension. Any severe, persistent or unexpected reaction warrants stopping the medicine and seeking clinical review.



